Camptodactyly: occurrence in two new genetic syndromes and its relationship to other syndromes.

New clinical and laboratory finding in anti-phospholipid syndromes

Antiphospholipid syndrome (APS) is a systemic autoimmune disease with the appearance of anti-phospholipid antibody (ACLA), Anti β2GPI and lupus anticoagulant (LAC) in serum. The antigen-antibody reaction on cell surface leads to thrombosis, miscarriage and inflammation. Clinical findings are diverse and include thrombosis in veins and arteries, pregnancy loss, thrombocytopenia, neurological and...

Dermatoglyphic Assessment in Down and Klinefelter Syndromes

Background: Dermatoglyphics are the dermal ridge configurations on the digits, palms and soles. Dermatoglyphic polymorphism results from the co-operation of genetic and environmental factors. The Dermatoglyphic analysis is a valuable completion of initial diagnosis of some syndromes genetically determined. Our objective was to assess dermatoglyphics study results against standard chromosomal an...

epileptic syndromes: from clinic to genetic.

epilepsy is one of the most common neurological disorders. studies have demonstrated that genetic factors have a strong role in etiology of epilepsy. mutations in genes encoding ion channels, neurotransmitters and other proteins involved in the neuronal biology have been recognized in different types of this disease. moreover, some chromosomal aberration including ring chromosomes will result i...

Malnutrition in the elderly and its relationship with other geriatric syndromes.

BACKGROUND & AIMS Age related decline in food intake is associated with various physiological, psychological and social factors. Our aim was to assess the nutritional status of our elderly patients and its association with other geriatric syndromes. METHODS In this cross-sectional population based study, Mini Nutritional Assessment (MNA) test was used to evaluate nutritional status of 413 eld...

Autism and Genetic Syndromes